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KMID : 0378019720150040136
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New Medical Journal
1972 Volume.15 No. 4 p.136 ~ p.142
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Experimental and Clinical Studies on Tooth Transplantation
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Abstract
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The field of tissue transplantation currently occupies a major position in experimental and clinical reseach. Much of the animal experimentation with respect to autogenous transplants has involved hamsters, monkeys, and dogs.
This investigation is primarily concerned with the fate of transplants that contain odontogenic tissue of autotransplantation and clinical application in human studies.
MATERIALS AND METHODS:
In autotransplantation experimental animal study, a tooth with incompletely formed roots was empl￢oyed; incisors in the identical corresponding positions of opposite arch of same jaw were exchanged as respective transplants. For example upper right first lateral incisor was removed and transplanted to upper left first lateral incisor socket and vice versa.
In autotransplantation experiments, 9 dogs of average age of 3 months old, with body weight rang￢ing from 3 to 6 kilograms were selected. The animals were weighed and anesthetized with 0.4cc. Halatal(Jensen-Salbery Laboratories) per Kilogram of body weight of individual dogs and additional local infiltrative anesthesia was performed. The surgical procedures were made in usual manner.
Those incisor teeth from both upper and lower which have undergone from 1/2 to 2/3 root formation were selected as transplants. The transplants with surrounding tissue were removed. fixed in 10% Formalin, decalcified, embedded in celloidine, sectioned, and stained with Hematoxylin-Eosin.
FINDINGS
Subsequently to the transplantation, macroscopic, roentgenographic, and microscopic examination have been made on all the transplants on 10th, 30th and 60th day.
Evidence revealed throughout this observation seems to indicate following conclusion:
1. Transplantation of tooth with incompletely formed roots in autotransplantation study revealed the fact that in 10 days subsequent to the implantation, marked hyperemia was noted in the pulp of teeth ; in 30 to 60th days edematous space and hemorrhage in the region of coronal pulp, and reticular atrophy and partly necrosis in the region of radicular pulp were evidenced.
2. No resorption and apposition of roots was noted. On 10th day in the auto-transplantation but
root resorption or cementum apposition were evident on 30th and 60th days.
CLINICAL CASE STUDY:
Case 1.
A korean girl, aged 16, came to the Oral Surgery Clinic complaining of an advanced carious lower right first permanent molar. Roentgenograms indicated the presence of apical areas of rarefaction on both mesial and distal roots.
Under mandibular block anesthesia long incision was begun about 1.5cm. distal to the second molar and extended to the distal side of the first bicuspid. At first, first molar was extracted and by the use of chisels, large surgical burs, curets, the first molar region was prepared to receive the trans￢plant. After removing the bone which buccal and occlusal to the unerupted third molar, this tooth was carefully elevated and placed immediately into the enlarged first molar socket. The buccal and lingual soft tissue flaps were approximated with interrupted 4-0 black silk sutures. And ligation to the lower right first molar site was performed. Postoperative antibiotics were given for a week.
Case 2.
A Korean girl, aged 16, complaining of advanced dental caries with periapical lesion of mandibular
right second molar. The surgical procedure was done in same as the above case. The transplant was splinted by acrylic resin plate.
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KEYWORD
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